Autoimmune Neurological Conditions

Infections of the Brain and Nervous System

Inflammatory conditions caused by viral, bacterial, and atypical pathogens

The central nervous system (CNS) is vulnerable to a range of infections that may involve the brain, spinal cord, or meninges. These conditions can be life-threatening and require prompt medical attention.

A key syndrome is Meningoencephalitis, caused by various pathogens:

  • HSV (Herpes Simplex Virus): Common cause of viral encephalitis with sudden onset and serious complications.
  • HIV-related Infections: May lead to chronic viral encephalitis or secondary CNS infections in immunocompromised individuals.
  • TB (Tuberculous Meningitis): Atypical bacterial cause with slow progression, more prevalent in developing regions.
  • Bacterial Infections: Includes Streptococcus pneumoniae and Neisseria meningitidis, leading to acute meningitis.
  • COVID-19 Related: May trigger autoimmune encephalitis or direct viral invasion of the CNS.
  • Other Rare Infections: Includes fungal, parasitic, or emerging viral infections, particularly in immunocompromised patients.

Diagnosis typically involves cerebrospinal fluid (CSF) analysis, MRI, and PCR testing. Treatment depends on the underlying pathogen and may include antivirals, antibiotics, antifungals, or corticosteroids.